AustralieFrV1, Main, Exploration, bibRecord, 00A128

A comparison of North American versus non-North American ADHD study populations

Identifieur interne : 00A128 ( Main/Exploration ); précédent : 00A127; suivant : 00A129

A comparison of North American versus non-North American ADHD study populations

Auteurs : Jan K. Buitelaar [Pays-Bas] ; Joanne Barton [Royaume-Uni] ; Marina Danckaerts [Belgique] ; Edgar Friedrichs [Allemagne] ; Christopher Gillberg [Suède] ; Philip L. Hazell [Australie] ; Hans Hellemans [Belgique] ; Mats Johnson [Suède] ; Luuk J. Kalverdijk [Pays-Bas] ; Gabriele Masi [Italie] ; David Michelson [États-Unis] ; Olivier Revol [France] ; Javier San Sebastian [Espagne] ; SHUYU ZHANG [États-Unis] ; Alessandro Zuddas [Italie]

Source :

European child & adolescent psychiatry [ 1018-8827 ] ; 2006.

RBID : Pascal:07-0084007

Descripteurs français

Pascal (Inist)
- Etude comparative, Hyperactivité, Trouble attention, Europe, Hyperkinésie, Amérique du Nord, Enfant, Trouble déficitaire de l'attention avec hyperactivité.
Wicri :
- topic : Enfant.

English descriptors

KwdEn :
- Attention disorder with hyperactivity, Attentional disorder, Child, Comparative study, Europe, Hyperactivity, Hyperkinesia, North America.

Abstract

Few large, prospective clinical studies in Europe have assessed the validity and applicability of research methods used to study ADHD in North America. To assess comparability of study populations, we examined baseline patient characteristics from a group of North American studies against those of a large European/African/Australian study. All studies used identical diagnostic assessments and inclusion criteria, with ADHD diagnosis and the presence of comorbid psychiatric conditions confirmed using the KSADS-PL. Raters were trained and assessed to ensure uniform diagnostic and symptom severity rating standards. Six hundred and four patients (mean age = 10.2 years) enrolled in the non-North American study, and 665 patients (mean age = 10.4 years) enrolled in the North American study. The proportion of girls was higher in the North American studies (29.2% vs. 10.4%, p < 0.001). In both groups, most patients had a positive family history of ADHD and previous stimulant treatment. Fewer had the inattentive subtype of ADHD, and mean severity was slightly higher in the non-North American study. Results demonstrate that, when a uniform set of rigorous, standardized diagnostic criteria are used by skilled clinicians, the patient populations identified are generally similar. This supports the practice of generalizing results from treatment studies across geographies.

Affiliations:

Allemagne, Australie, Belgique, Espagne, France, Italie, Pays-Bas, Royaume-Uni, Suède, États-Unis
Auvergne-Rhône-Alpes, Communauté de Madrid, Groningue (province), Rhône-Alpes, Toscane
Groningue, Lyon, Madrid, Pise
Université de Pise

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Le document en format XML

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<s3>ITA</s3>
<sZ>15 aut.</sZ>
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<wicri:noRegion>Dept. of Neuroscience University of Cagliari</wicri:noRegion>
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<front><div type="abstract" xml:lang="en">Few large, prospective clinical studies in Europe have assessed the validity and applicability of research methods used to study ADHD in North America. To assess comparability of study populations, we examined baseline patient characteristics from a group of North American studies against those of a large European/African/Australian study. All studies used identical diagnostic assessments and inclusion criteria, with ADHD diagnosis and the presence of comorbid psychiatric conditions confirmed using the KSADS-PL. Raters were trained and assessed to ensure uniform diagnostic and symptom severity rating standards. Six hundred and four patients (mean age = 10.2 years) enrolled in the non-North American study, and 665 patients (mean age = 10.4 years) enrolled in the North American study. The proportion of girls was higher in the North American studies (29.2% vs. 10.4%, p < 0.001). In both groups, most patients had a positive family history of ADHD and previous stimulant treatment. Fewer had the inattentive subtype of ADHD, and mean severity was slightly higher in the non-North American study. Results demonstrate that, when a uniform set of rigorous, standardized diagnostic criteria are used by skilled clinicians, the patient populations identified are generally similar. This supports the practice of generalizing results from treatment studies across geographies.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Communauté de Madrid</li>
<li>Groningue (province)</li>
<li>Rhône-Alpes</li>
<li>Toscane</li>
</region>
<settlement><li>Groningue</li>
<li>Lyon</li>
<li>Madrid</li>
<li>Pise</li>
</settlement>
<orgName><li>Université de Pise</li>
</orgName>
</list>
<tree><country name="Pays-Bas"><noRegion><name sortKey="Buitelaar, Jan K" sort="Buitelaar, Jan K" uniqKey="Buitelaar J" first="Jan K." last="Buitelaar">Jan K. Buitelaar</name>
</noRegion>
<name sortKey="Kalverdijk, Luuk J" sort="Kalverdijk, Luuk J" uniqKey="Kalverdijk L" first="Luuk J." last="Kalverdijk">Luuk J. Kalverdijk</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Barton, Joanne" sort="Barton, Joanne" uniqKey="Barton J" first="Joanne" last="Barton">Joanne Barton</name>
</noRegion>
</country>
<country name="Belgique"><noRegion><name sortKey="Danckaerts, Marina" sort="Danckaerts, Marina" uniqKey="Danckaerts M" first="Marina" last="Danckaerts">Marina Danckaerts</name>
</noRegion>
<name sortKey="Hellemans, Hans" sort="Hellemans, Hans" uniqKey="Hellemans H" first="Hans" last="Hellemans">Hans Hellemans</name>
</country>
<country name="Allemagne"><noRegion><name sortKey="Friedrichs, Edgar" sort="Friedrichs, Edgar" uniqKey="Friedrichs E" first="Edgar" last="Friedrichs">Edgar Friedrichs</name>
</noRegion>
</country>
<country name="Suède"><noRegion><name sortKey="Gillberg, Christopher" sort="Gillberg, Christopher" uniqKey="Gillberg C" first="Christopher" last="Gillberg">Christopher Gillberg</name>
</noRegion>
<name sortKey="Johnson, Mats" sort="Johnson, Mats" uniqKey="Johnson M" first="Mats" last="Johnson">Mats Johnson</name>
</country>
<country name="Australie"><noRegion><name sortKey="Hazell, Philip L" sort="Hazell, Philip L" uniqKey="Hazell P" first="Philip L." last="Hazell">Philip L. Hazell</name>
</noRegion>
</country>
<country name="Italie"><region name="Toscane"><name sortKey="Masi, Gabriele" sort="Masi, Gabriele" uniqKey="Masi G" first="Gabriele" last="Masi">Gabriele Masi</name>
</region>
<name sortKey="Zuddas, Alessandro" sort="Zuddas, Alessandro" uniqKey="Zuddas A" first="Alessandro" last="Zuddas">Alessandro Zuddas</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Michelson, David" sort="Michelson, David" uniqKey="Michelson D" first="David" last="Michelson">David Michelson</name>
</noRegion>
<name sortKey="Shuyu Zhang" sort="Shuyu Zhang" uniqKey="Shuyu Zhang" last="Shuyu Zhang">SHUYU ZHANG</name>
</country>
<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Revol, Olivier" sort="Revol, Olivier" uniqKey="Revol O" first="Olivier" last="Revol">Olivier Revol</name>
</region>
</country>
<country name="Espagne"><region name="Communauté de Madrid"><name sortKey="San Sebastian, Javier" sort="San Sebastian, Javier" uniqKey="San Sebastian J" first="Javier" last="San Sebastian">Javier San Sebastian</name>
</region>
</country>
</tree>
</affiliations>
</record>

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A comparison of North American versus non-North American ADHD study populations

A comparison of North American versus non-North American ADHD study populations

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